The RCC1 Polyclonal Antibody (CAB0662) is specially crafted for researchers studying RCC1, a protein known for its essential role in cell division. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RCC1 protein, this antibody facilitates the detection and analysis of RCC1 in various cell types, making it an invaluable tool for investigations in cellular biology and cancer research.RCC1, also referred to as regulator of chromosome condensation 1, is crucial for the proper regulation of the cell cycle and nuclear envelope dynamics.
Dysregulation of RCC1 has been linked to various cancers and developmental disorders, highlighting its significance in cellular processes. Researchers aiming to delve deeper into the mechanisms of cell division and disease progression can benefit from the use of this antibody to enhance their understanding of RCC1's functions and potential therapeutic targets.
Product Name:
RCC1 Rabbit Monoclonal Antibody
SKU:
CAB0662
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RCC1 (P18754).
Enables several functions, including guanyl-nucleotide exchange factor activity; nucleosomal DNA binding activity; and protein heterodimerization activity. Involved in several processes, including G1/S transition of mitotic cell cycle; regulation of mitotic nuclear division; and spindle organization. Located in chromatin; cytoplasm; and nucleus. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
1104
Clone Number:
ARC1834
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using RCC1 Rabbit mAb (CAB0662) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
