The RCAN2 Polyclonal Antibody (PAC011777) is a valuable tool for research involving RCAN2, a protein involved in regulating cell growth, development, and immune response. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the RCAN2 protein, researchers can easily detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.RCAN2, also known as Regulator of Calcineurin 2, plays a crucial role in modulating cellular processes and signaling pathways, making it a key player in various physiological and pathological conditions.
Its involvement in immune regulation and cell proliferation implicates RCAN2 in diseases such as cancer, cardiovascular disorders, and neurodegenerative diseases. By investigating the function of RCAN2, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets in these areas.Overall, the RCAN2 Polyclonal Antibody offers researchers a reliable tool for studying the role of RCAN2 in physiological and pathological processes, ultimately advancing our understanding of complex diseases and paving the way for targeted therapeutic interventions.
regulator of calcineurin 2;RCAN2;CSP2;DSCR1L1;MCIP2;RCN2;ZAKI-4;ZAKI4;hRCN2 ;
UniProt Protein Function:
RCAN2: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs to the RCAN family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6p12.3Cellular Component: cytoplasmMolecular Function: calcium-dependent protein serine/threonine phosphatase regulator activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Down syndrome candidate region 1-like 1; Myocyte-enriched calcineurin-interacting protein 2; MCIP2; Regulator of calcineurin 2; Thyroid hormone-responsive protein ZAKI-4
