RBPJK Rabbit Polyclonal Antibody (CAB5675)
- SKU:
- CAB5675
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RBPJK Rabbit Polyclonal Antibody |
SKU: | CAB5675 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RBPJKK (NP_976028.1). |
Sequence: | MGGC RKFG ERPP PKRL TREA MRNY LKER GDQT VLIL HAKV AQKS YGNE KRFF CPPP CVYL MGSG WKKK KEQM ERDG CSEQ ESQP CAFI GIGN SDQE MQQL NLEG KNYC TAKT LYIS DSDK RKHF MLSV KMFY GNSD DIGV FLSK RIKV ISKP SKKK QSLK NADL CIAS GTKV ALFN RLRS QTVS TRYL HVEG GNFH ASSQ QWGA FFIH LLDD DESE GEEF TVRD GYIH YGQT VKLV CSVT GMAL PRLI IRKV DKQT ALLD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SUH; csl; AOS3; CBF1; KBF2; CBF-1; RBP-J; RBPJK; IGKJRB; RBP-JK; RBPSUH; IGKJRB1; RBP-J kappa |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 56kDa |
Observed MW: | 61kDa |
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
Purification Method: | Affinity purification |
Gene ID: | 3516 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |