The RBP2 Polyclonal Antibody (CAB6717) is specifically designed for researchers studying RBP2, a key regulator of gene expression involved in various cellular processes. Raised in rabbits, this antibody demonstrates high reactivity with human samples and has been validated for use in Western blot applications. It targets the RBP2 protein, enabling accurate detection and analysis in a variety of cell types, making it an ideal tool for investigations in molecular biology and cancer research.RBP2, also known as Retinoblastoma-binding protein 2, plays a crucial role in epigenetic regulation by controlling gene expression through histone demethylation.
Its involvement in cell differentiation, proliferation, and metabolism highlights its significance in various biological pathways. Understanding the function of RBP2 is essential for unraveling its impact on diseases such as cancer, developmental disorders, and metabolic dysfunction. By studying RBP2, researchers can gain insights into potential therapeutic targets for addressing these conditions.
Product Name:
RBP2 Rabbit Polyclonal Antibody
SKU:
CAB6717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human RBP2 (NP_004155.2).
This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle.
Purification Method:
Affinity purification
Gene ID:
5948
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RBP2 antibody (CAB6717) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
