Anti-RBMY1A1 Antibody (CAB18376)
- SKU:
- CAB18376
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Anti-RBMY1A1 Antibody (CAB18376)
The Rabmy1A1 Polyclonal Antibody (CAB18376) is specifically designed for research involving the Rabmy1A1 protein, a key regulator of vesicle trafficking and membrane fusion processes within cells. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blotting and immunofluorescence microscopy.Rabmy1A1 is a member of the Rab family of small GTPases, which play essential roles in cellular transport and signaling pathways. Studies have shown that Rabmy1A1 is involved in the regulation of intracellular vesicle trafficking, particularly in the endosomal-lysosomal system.
Its function in these processes makes it a crucial target for research in cell biology and molecular biology.By using the Rabmy1A1 Polyclonal Antibody, researchers can effectively detect and analyze the expression and localization of Rabmy1A1 in different cell types and experimental conditions. This antibody enables detailed studies on the function and regulation of Rabmy1A1, providing valuable insights into the mechanisms underlying cellular transport and membrane dynamics. Its versatility and specificity make it a valuable tool for investigating various biological processes related to vesicle trafficking and organelle function.
| Antibody Name: | Anti-RBMY1A1 Antibody |
| Antibody SKU: | CAB18376 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RBMY1A1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human RBMY1A1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5940 |
| Uniprot: | P0DJD3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | RBM, RBM1, RBM2, RBMY, RBMY1C, YRRM1, YRRM2, RBMY1A1 |
| Background: |
| UniProt Protein Function: | RBMY1A1: RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs. Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3. |
| UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: Yq11.223 Molecular Function:mRNA binding; protein binding Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome Disease: Spermatogenic Failure, Y-linked, 2 |
| NCBI Summary: | This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016] |
| UniProt Code: | P0DJD3 |
| NCBI GenInfo Identifier: | 1004170692 |
| NCBI Gene ID: | 5940 |
| NCBI Accession: | NP_001307873.1 |
| UniProt Secondary Accession: | P0DJD3,Q15376, Q15377, Q15414, Q6NSB5, Q86VU6, Q8NHR0 |
| UniProt Related Accession: | P0DJD3 |
| Molecular Weight: | 55.4kD |
| NCBI Full Name: | RNA-binding motif protein, Y chromosome, family 1 member A1 isoform 2 |
| NCBI Synonym Full Names: | RNA binding motif protein, Y-linked, family 1, member A1 |
| NCBI Official Symbol: | RBMY1A1Â Â |
| NCBI Official Synonym Symbols: | RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1CÂ Â |
| NCBI Protein Information: | RNA-binding motif protein, Y chromosome, family 1 member A1 |
| UniProt Protein Name: | RNA-binding motif protein, Y chromosome, family 1 member A1 |
| UniProt Synonym Protein Names: | RNA-binding motif protein 1; RNA-binding motif protein 2; Y chromosome RNA recognition motif 1; hRBMY |
| Protein Family: | RNA-binding motif protein |
| UniProt Gene Name: | RBMY1A1Â Â |
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