The RBMX Polyclonal Antibody (CAB15436) is a valuable tool for researchers studying the RNA-binding protein RBMX, which plays a key role in RNA metabolism and splicing. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting RBMX in human samples and is validated for use in Western blot applications.RBMX is known to be involved in various cellular processes, including mRNA processing and transport, making it a critical player in gene expression regulation. Dysregulation of RBMX has been linked to diseases such as cancer, neurodegenerative disorders, and developmental abnormalities, highlighting its significance as a potential therapeutic target.
By utilizing the RBMX Polyclonal Antibody, researchers can gain insights into the function and expression levels of RBMX in different cell types and tissues, ultimately advancing our understanding of RNA biology and its implications in disease pathogenesis. This antibody is a valuable asset for studies in molecular biology, oncology, and neuroscience, offering researchers a reliable tool for their experiments.
Product Name:
RBMX Rabbit Polyclonal Antibody
SKU:
CAB15436
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human RBMX/hnRNP G (NP_002130.2).
RNMX; HNRPG; HNRNPG; MRXS11; RBMXP1; RBMXRT; hnRNP-G; RBMX/hnRNP G
Positive Sample:
Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
42kDa
Observed MW:
42kDa
This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns.
Purification Method:
Affinity purification
Gene ID:
27316
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using RBMX/hnRNP G antibody (CAB15436) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
