The RBM5 Polyclonal Antibody (CAB10788) is a valuable tool for researchers studying RNA-binding motif protein 5 (RBM5), a key player in RNA metabolism and regulation. This antibody, produced in rabbits, boasts high specificity and sensitivity for RBM5 in human samples, making it an ideal choice for Western blot applications.RBM5 is known for its role in alternative splicing and has been implicated in various cancer types, making it an important target for cancer research. The RBM5 Polyclonal Antibody enables precise detection and analysis of RBM5 protein levels in different cell types, facilitating investigations into its function and potential therapeutic applications.
By understanding the function of RBM5, researchers can gain insights into its impact on RNA processing and potentially uncover new mechanisms for cancer development and progression. The RBM5 Polyclonal Antibody provides a reliable tool for exploring the role of RBM5 in cancer biology and advancing our knowledge of RNA-mediated regulatory pathways.
Product Name:
RBM5 Rabbit Polyclonal Antibody
SKU:
CAB10788
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBM5 (NP_005769.1).
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
Purification Method:
Affinity purification
Gene ID:
10181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBM5 Rabbit pAb (CAB10788) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
