The RBM4B Polyclonal Antibody (CAB14682) is specifically designed for researchers studying the RBM4B protein, a key regulator of alternative splicing in RNA processing. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the RBM4B protein, this antibody enables precise detection and analysis in various cell types, making it a valuable tool for studies in molecular biology and gene expression.RBM4B is a critical factor in the regulation of RNA splicing, and its dysregulation has been linked to various diseases, including cancer and neurological disorders.
By understanding the role of RBM4B in alternative splicing, researchers can gain insights into disease mechanisms and potentially identify novel therapeutic targets. The RBM4B Polyclonal Antibody is essential for investigating the functions of RBM4B and its implications in disease pathology, offering a promising avenue for innovative research and drug development.
Product Name:
RBM4B Rabbit Polyclonal Antibody
SKU:
CAB14682
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-359 of human RBM4B (NP_113680.1).
Enables RNA binding activity. Predicted to be involved in entrainment of circadian clock by photoperiod; mRNA splicing, via spliceosome; and regulation of gene expression. Predicted to act upstream of or within positive regulation of gene expression. Located in cytosol and nucleoplasm. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
83759
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBM4B Rabbit pAb (CAB14682) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
