The RBM39 Polyclonal Antibody (CAB15760) is a valuable tool for researchers studying RNA-binding motif protein 39 (RBM39), a protein involved in RNA processing and gene expression regulation. This antibody, raised in rabbits, is highly specific for RBM39 and is validated for use in various applications including Western blot and immunohistochemistry.RBM39 is known to play a critical role in alternative splicing of pre-mRNA, which can impact gene expression and protein diversity. Dysregulation of RBM39 has been implicated in various diseases including cancer, making it a promising target for therapeutic interventions.
The RBM39 Polyclonal Antibody enables researchers to detect and analyze RBM39 levels in different cell types and tissues, providing valuable insights into its function and potential implications in disease pathology.By using the RBM39 Polyclonal Antibody, researchers can uncover new information about the role of RBM39 in RNA processing and gene regulation, advancing our understanding of its impact on cellular functions and disease development. This antibody is a valuable tool for studies in molecular biology, cancer research, and other fields where RNA processing and gene expression play a critical role.
Product Name:
RBM39 Rabbit Polyclonal Antibody
SKU:
CAB15760
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-508 of human RBM39 (NP_001229528.1).
This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X.
Purification Method:
Affinity purification
Gene ID:
9584
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBM39 Rabbit pAb (CAB15760) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
