The RBM3 Polyclonal Antibody (CAB5931) is a powerful tool for researchers studying RBM3, a protein that plays a crucial role in regulating gene expression and promoting cell survival under stress conditions. This antibody, generated in rabbits, exhibits high specificity and sensitivity for RBM3 in human samples, making it an ideal choice for Western blot applications.RBM3 is known for its ability to enhance the translation of specific mRNAs, leading to increased protein production and cell viability in response to cold shock, hypoxia, and other cellular stressors. Its role in promoting cell survival has important implications for research in areas such as cancer, neurodegenerative diseases, and ischemic injury.
By targeting RBM3 with this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying stress adaptation and cell resilience, potentially uncovering new therapeutic strategies for diseases characterized by aberrant gene expression and cell death. This antibody is a valuable tool for studies aiming to elucidate the complex functions of RBM3 and its potential as a therapeutic target in various pathological conditions.
Product Name:
RBM3 Rabbit Polyclonal Antibody
SKU:
CAB5931
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-157 of human RBM3 (NP_006734.1).
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria.
Purification Method:
Affinity purification
Gene ID:
5935
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBM3 Rabbit pAb (CAB5931) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
