The RBM3 Polyclonal Antibody (CAB19967) is a powerful tool for researchers studying RNA Binding Motif Protein 3 (RBM3), a protein known for its role in regulating gene expression and promoting cell survival under stress conditions. This antibody, produced in rabbits, specifically targets RBM3 and has been validated for use in various applications, including Western blotting.RBM3 is a key player in cellular stress response mechanisms, making it a promising target for studies related to cancer, neurodegenerative diseases, and other conditions involving cellular stress.
By using this antibody, researchers can effectively detect and analyze RBM3 in different cell types, facilitating a deeper understanding of its functions and potential therapeutic applications.Overall, the RBM3 Polyclonal Antibody is a valuable tool for investigating the role of RBM3 in cellular processes and disease pathogenesis, offering new insights and opportunities for targeted research in the fields of molecular biology and biomedicine.
Product Name:
[KO Validated] RBM3 Rabbit Polyclonal Antibody
SKU:
CAB19967
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-157 of human RBM3 (NP_006734.1).
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria.
Purification Method:
Affinity purification
Gene ID:
5935
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and RBM3 knockout (KO) 293T cells, using [KO Validated] RBM3 Rabbit pAb (CAB19967) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
