The RBM11 Polyclonal Antibody (CAB13216) is a crucial tool for researchers studying RBM11, a RNA-binding protein associated with various cellular processes. This highly specific antibody, generated in rabbits, is optimized for use in Western blot applications and is particularly reactive with human samples.RBM11 plays a key role in post-transcriptional gene regulation, with implications in mRNA splicing, stability, and translation. Its dysregulation has been linked to diseases like cancer, neurodegenerative disorders, and developmental abnormalities.
The ability to detect and analyze RBM11 expression in various cell types makes this antibody essential for investigations into RNA biology and disease pathology.By targeting RBM11, researchers can unravel the molecular mechanisms underlying gene expression control and potentially identify novel therapeutic targets for a range of diseases. The validation of this antibody for specific applications ensures reliable and accurate results, supporting advancements in biomedical research.
Product Name:
RBM11 Rabbit Polyclonal Antibody
SKU:
CAB13216
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human RBM11 (NP_658983.3).
Enables poly(U) RNA binding activity and protein homodimerization activity. Acts upstream of or within cellular response to oxidative stress and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck.
Purification Method:
Affinity purification
Gene ID:
54033
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBM11 Rabbit pAb (CAB13216) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
