The RBM10 Polyclonal Antibody (CAB4209) is a valuable tool for researchers studying RBM10, a key RNA binding protein involved in RNA processing and splicing. This antibody, produced in rabbits, is highly specific for RBM10 and has been validated for use in Western blot applications. By binding to RBM10, this antibody allows for detection and analysis of RBM10 expression in various cell types, making it ideal for studies in molecular biology and cancer research.RBM10 plays a crucial role in regulating alternative splicing and gene expression, making it a critical player in controlling cell function and development.
Dysregulation of RBM10 has been implicated in various diseases, including cancer and neurological disorders, highlighting the importance of understanding its function and regulation. By using the RBM10 Polyclonal Antibody, researchers can gain insights into the role of RBM10 in disease progression and potentially identify novel therapeutic targets.
Product Name:
RBM10 Rabbit Polyclonal Antibody
SKU:
CAB4209
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human RBM10 (NP_005667.2).
This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8241
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RBM10 antibody (CAB4209) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
