The RBL2 Polyclonal Antibody (CAB13649) is a vital tool for research involving RBL2, a key regulator of cell cycle progression and tumor suppression. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RBL2 protein, researchers can accurately detect and analyze RBL2 expression in a variety of cell types, making it ideal for studies in cancer biology and cell cycle regulation.RBL2, also known as retinoblastoma-like protein 2, plays a crucial role in controlling cell growth and proliferation by inhibiting the activity of cell cycle-promoting factors.
Its role as a tumor suppressor gene makes it a potential target for therapeutic interventions in cancer treatment and prevention. Understanding the function of RBL2 is essential for developing strategies to manipulate cell cycle progression and limit abnormal cell proliferation in cancer and other diseases.Overall, the RBL2 Polyclonal Antibody (CAB13649) offers researchers a valuable tool for investigating the role of RBL2 in cell cycle regulation and tumor suppression, providing insights that may lead to the development of novel therapeutic approaches for cancer and other diseases involving abnormal cell growth.
Product Name:
RBL2 Rabbit Polyclonal Antibody
SKU:
CAB13649
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 413-613 of human RBL2 (NP_005602.3).
Enables promoter-specific chromatin binding activity. Involved in regulation of lipid kinase activity. Acts upstream of or within negative regulation of gene expression. Located in chromosome; cytosol; and nuclear lumen.
Purification Method:
Affinity purification
Gene ID:
5934
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Neuro-2a cells, using RBL2 antibody (CAB13649) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
