RBKS Antibody (PACO29388)
- SKU:
- PACO29388
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
RBKS Antibody (PACO29388)
The RBKS Polyclonal Antibody (PAC029388) is a valuable tool for researchers studying the RBKS protein, a key enzyme involved in the pentose phosphate pathway. This antibody, generated in rabbits, exhibits high specificity and sensitivity for RBKS in a variety of sample types, particularly human samples.RBKS plays a crucial role in cellular metabolism by catalyzing the conversion of ribose-5-phosphate to ribulose-5-phosphate, a critical step in the production of pentose sugars and NADPH. Dysregulation of the pentose phosphate pathway, in which RBKS is a key player, has been implicated in various diseases, including cancer and metabolic disorders.
Validated for use in Western blot applications, the RBKS Polyclonal Antibody allows for precise detection and analysis of RBKS protein levels in different cell types, making it an ideal tool for investigations into cellular metabolism, bioenergetics, and disease pathology. This antibody can provide valuable insights into the role of RBKS in health and disease, offering potential targets for therapeutic interventions.
| Antibody Name: | RBKS Antibody (PACO29388) |
| Antibody SKU: | PACO29388 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Ribokinase protein (2-322AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: Rat brain tissue, Rat liver tissue All lanes: RBKS antibody at 3.4µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 35, 31 kDa Observed band size: 35 kDa . |
 | Immunohistochemistry analysis of human testis tissue using PACO29388 at dilution of 1:100. |
 | Immunohistochemistry analysis of human liver cancer using PACO29388 at dilution of 1:100. |
| Background: | extracellular exosome |
| Synonyms: | Ribokinase (RK) (EC 2.7.1.15), RBKS, RBSK |
| UniProt Protein Function: | Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
| UniProt Code: | Q9H477 |
| NCBI GenInfo Identifier: | 20139730 |
| NCBI Gene ID: | 64080 |
| NCBI Accession: | Q9H477.1 |
| UniProt Secondary Accession: | Q9H477,A9UK04, B4DV96 |
| UniProt Related Accession: | Q9H477 |
| Molecular Weight: | 30,361 Da |
| NCBI Full Name: | Ribokinase |
| NCBI Synonym Full Names: | ribokinase |
| NCBI Official Symbol: | RBKSÂ Â |
| NCBI Official Synonym Symbols: | RK; RBSKÂ Â |
| NCBI Protein Information: | ribokinase |
| UniProt Protein Name: | Ribokinase |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | RBKSÂ Â |
| UniProt Entry Name: | RBSK_HUMAN |
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