NeuN Rabbit Polyclonal Antibody (CAB15959)
- SKU:
- CAB15959
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NeuN Rabbit Polyclonal Antibody |
SKU: | CAB15959 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NeuN (NP_001076044.1). |
Sequence: | MAQP YPPA QYPP PPQN GIPA EYAP PPPH PTQD YSGQ TPVP TEHG MTLY TPAQ THPE QPGS EAST QPIA GTQT VPQT DEAA QTDS QPLH PSDP TEKQ QPKR LHVS NIPF RFRD PDLR QMFG QFGK ILDV EIIF NERG SKGF GFVT FETS SDAD RARE KLNG TIVE GRKI EVNN ATAR VMTN KKTG NPYT NGWK LNPV VGAV YGPE FYAV TGFP YPTT GTAV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | FOX3; NEUN; FOX-3; HRNBP3; NeuN |
Positive Sample: | U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 34kDa |
Observed MW: | 54kDa |
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 146713 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |