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[KO Validated] NeuN Rabbit Polyclonal Antibody (CAB0951)

SKU:
CAB0951
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • KO Validated Antibodies 1 Anti-NeuN Antibody CAB0951KO Validated
  • KO Validated Antibodies 1 Anti-NeuN Antibody CAB0951KO Validated
  • KO Validated Antibodies 1 Anti-NeuN Antibody CAB0951KO Validated
  • KO Validated Antibodies 1 Anti-NeuN Antibody CAB0951KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] NeuN Rabbit Polyclonal Antibody
SKU:CAB0951
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of NeuN (NP_001076044.1).
Sequence:MAQP YPPA QYPP PPQN GIPA EYAP PPPH PTQD YSGQ TPVP TEHG MTLY TPAQ THPE QPGS EAST QPIA GTQT VPQT DEAA QTDS QPLH PSDP TEKQ QPKR LHVS NIPF RFRD PDLR QMFG QFGK ILDV EIIF NERG SKGF GFVT FETS SDAD RARE KLNG TIVE GRKI EVNN ATAR VMTN KKTG NPYT NGWK LNPV VGAV YGPE FYAV TGFP YPTT GTAV
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:FOX3; NEUN; FOX-3; HRNBP3; NeuN
Positive Sample:Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:34kDa
Observed MW:46-55kDa

This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Purification Method:Affinity purification
Gene ID:146713
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NeuN Rabbit pAb (CAB0951) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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