The RBBP8 Polyclonal Antibody (CAB10201) is a powerful tool for researchers studying the RBBP8 protein, also known as CtIP. CtIP plays a crucial role in DNA repair and cell cycle regulation, making it a key player in maintaining genomic stability. This antibody, generated in rabbits, has high specificity and sensitivity for detecting RBBP8 in human samples, making it ideal for Western blot applications.By targeting the RBBP8 protein, this antibody allows for the detection and analysis of CtIP levels in various cell types, providing valuable insights into DNA repair mechanisms and cell cycle control.
Its reliability and accuracy make it a valuable asset for research in fields such as cancer biology, genomics, and cell signaling pathways.The RBBP8 Polyclonal Antibody is a valuable tool for scientists looking to unravel the intricate functions of CtIP and its role in maintaining genome integrity. Its versatility and efficacy make it a valuable addition to any research lab investigating DNA repair processes and cell cycle regulation.
Product Name:
RBBP8 Rabbit Polyclonal Antibody
SKU:
CAB10201
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 648-897 of human RBBP8 (NP_002885.1).
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Purification Method:
Affinity purification
Gene ID:
5932
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Rat thymus, using RBBP8 antibody (CAB10201) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
