RBBP8 Rabbit Polyclonal Antibody (CAB10201)
- SKU:
- CAB10201
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | RBBP8 Rabbit Polyclonal Antibody |
SKU: | CAB10201 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 648-897 of human RBBP8 (NP_002885.1). |
Sequence: | VSFE NIQW SIDP GADL SQYK MDVT VIDT KDGS QSKL GGET VDMD CTLV SETV LLKM KKQE QKGE KSSN EERK MNDS LEDM FDRT THEE YESC LADS FSQA ADEE EELS TATK KLHT HGDK QDKV KQKA FVEP YFKG DERE TSLQ NFPH IEVV RKKE ERRK LLGH TCKE CEIY YADM PAEE REKK LASC SRHR FRYI PPNT PENF WEVG FPST QTCM ERGY IKED LDPC PRPK RRQP YNAI FSPK GKEQ KT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | RIM; COM1; CTIP; JWDS; SAE2; JAWAD; SCKL2; RBBP8 |
Positive Sample: | Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 102kDa |
Observed MW: | 110kDa |
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Purification Method: | Affinity purification |
Gene ID: | 5932 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |