The RBBP6 Polyclonal Antibody (CAB14776) is a valuable tool for researchers studying the RBBP6 protein, which plays a role in various cellular processes including chromatin remodeling, transcriptional regulation, and DNA repair. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.RBBP6 is a multifunctional protein involved in diverse biological pathways, making it a compelling target for investigation in fields such as cancer biology, gene regulation, and epigenetics.
By specifically binding to the RBBP6 protein, this antibody enables precise detection and analysis of its presence in various cell types.Research into RBBP6 has yielded insights into its potential role in tumorigenesis, DNA damage response, and gene expression regulation. By studying the function and regulation of RBBP6, researchers can gain a better understanding of its impact on cellular processes and its potential as a therapeutic target in cancer and other diseases.
Product Name:
RBBP6 Rabbit Polyclonal Antibody
SKU:
CAB14776
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1240-1355 of human RBBP6 (NP_008841.2).
Chromosome, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, nucleolus.
Calculated MW:
202kDa
Observed MW:
210kDa
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5930
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of K-562 cells, using RBBP6 antibody (CAB14776) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
