RBBP5 Rabbit Polyclonal Antibody (CAB6965)
- SKU:
- CAB6965
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RBBP5 Rabbit Polyclonal Antibody |
SKU: | CAB6965 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 319-538 of human RBBP5 (NP_005048.2). |
Sequence: | SIWA QNQV ENWS AFAP DFKE LDEN VEYE ERES EFDI EDED KSEP EQTG ADAA EDEE VDVT SVDP IAAF CSSD EELE DSKA LLYL PIAP EVED PEEN PYGP PPDA VQTS LMDE GASS EKKR QSSA DGSQ PPKK KPKT TNIE LQGV PNDE VHPL LGVK GDGK SKKK QAGR PKGS KGKE KDSP FKPK LYKG DRGL PLEG SAKG KVQA ELSQ PLTA GGAI SELL |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | RBQ3; SWD1; RBBP5 |
Positive Sample: | MCF7,NCI-H460,HeLa,Mouse spleen,Mouse brain,Mouse thymus,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 59kDa |
Observed MW: | 70kDa |
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5929 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |