[KO Validated] RBBP4 Rabbit Polyclonal Antibody (CAB13934)
- SKU:
- CAB13934
- Product Type:
- Antibody
- Applications:
- WB
- IF
- IP
- ChIP
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
Product Name: | [KO Validated] RBBP4 Rabbit Polyclonal Antibody |
SKU: | CAB13934 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human RBBP4 (NP_005601.1). |
Sequence: | MADK EAAF DDAV EERV INEE YKIW KKNT PFLY DLVM THAL EWPS LTAQ WLPD VTRP EGKD FSIH RLVL GTHT SDEQ NHLV IASV QLPN DDAQ FDAS HYDS EKGE FGGF GSVS GKIE IEIK INHE GEVN RARY MPQN PCII ATKT PSSD VLVF DYTK HPSK PDPS GECN PDLR LRGH QKEG YGLS WNPN LSGH LLSA SDDH TICL WDIS AVPK EGKV VDAK TIFT GHTA VVED VSWH LLHE SLFG SVAD DQKL MIWD TRSN NTSK PSHS VDAH TAEV NCLS FNPY SEFI LATG SADK TVAL WDLR NLKL KLHS FESH KDEI FQVQ WSPH NETI LASS GTDR RLNV WDLS KIGE EQSP EDAE DGPP ELLF IHGG HTAK ISDF SWNP NEPW VICS VSED NIMQ VWQM AENI YNDE DPEG SVDP EGQG S |
Tested Applications: | WB ChIP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 ChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | NURF55; RBAP48; lin-53; P4 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5928 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |