The RB Rabbit Polyclonal Antibody (CAB17005) is a powerful tool for researchers interested in studying the role of CD300A in immune regulation. CD300A is a cell surface molecule known for its ability to inhibit immune responses, making it a key player in immune homeostasis. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the CD300A protein, this antibody enables researchers to detect and analyze CD300A expression in various cell types, making it an ideal choice for studies in immunology and cancer research.
The CD300A Polyclonal Antibody can help researchers gain valuable insights into the function of CD300A in immune response modulation, making it a valuable tool for investigating diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By understanding the activity of CD300A, researchers can work towards developing therapies that harness or modulate immune function in these disease contexts.
Product Name:
RB Rabbit Polyclonal Antibody
SKU:
CAB17005
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 701-928 of human RB (NP_000312.2).
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Purification Method:
Affinity purification
Gene ID:
5925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using RB Rabbit pAb (CAB17005) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
