The Raver1 Polyclonal Antibody (CAB13138) is a valuable tool for researchers studying the Raver1 protein, a key regulator of alternative splicing. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.Raver1 is essential for maintaining proper splicing patterns, which play a critical role in gene expression and protein diversity. Dysregulation of alternative splicing has been linked to various diseases, including cancer and neurological disorders. By targeting Raver1, researchers can gain insight into how changes in splicing patterns contribute to disease progression and potentially identify new therapeutic targets.
With its specificity for Raver1, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it a valuable tool for studies in molecular biology and disease research. By understanding the functions of Raver1, researchers can advance our knowledge of gene regulation and potentially develop novel strategies for treating splicing-related diseases.
Product Name:
RAVER1 Rabbit Polyclonal Antibody
SKU:
CAB13138
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 390-490 of human RAVER1 (NP_597709.2).
Enables RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
125950
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAVER1 Rabbit pAb (CAB13138) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
