Rat Interleukin-2/IL-2 Recombinant Protein (His Tag) (RPES6140)
- SKU:
- RPES6140
- Product Type:
- Recombinant Protein
- Species:
- Rat
Description
| Product Name: | Rat Interleukin-2/IL-2 Recombinant Protein (His Tag) |
| Product Code: | RPES6140 |
| Size: | 20µg |
| Species: | Rat |
| Expression Host: | HEK293 Cells |
| Synonyms: | Aldesleukin, IL 2, IL-2, IL2, IL2, Interleukin 2, Interleukin-2, Involved in regulation of T cell clonal expansion, Lymphokine, POIL2, T Cell Growth Factor, T-cell growth factor, TCGF |
| Mol Mass: | 14.74 kDa |
| AP Mol Mass: | 16 kDa |
| Tag: | C-His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Bio Activity: | Testing in progress |
| Sequence: | Ala 21-Gln 155 |
| Accession: | P17108 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. |
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