The RASSF8 Polyclonal Antibody (PAC011738) is specifically designed for researchers studying the RASSF8 protein, a member of the Ras association domain family known for its tumor-suppressing properties. This antibody, generated in rabbits, is highly sensitive and reactive towards human samples, making it a valuable tool for Western blot applications.RASSF8 is involved in various cellular processes, including cell proliferation, apoptosis, and cell cycle regulation. Its role as a tumor suppressor makes it a promising target for cancer research.
By targeting the RASSF8 protein, researchers can gain insights into its function and potential as a therapeutic target in cancer treatment.This antibody enables the detection and analysis of RASSF8 in different cell types, allowing for detailed studies in oncology and molecular biology. Understanding the mechanisms behind RASSF8 activity is essential for uncovering its full potential in cancer therapy and personalized medicine strategies.
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8;RASSF8;C12orf2;HoJ-1 ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
