The RASSF8 Polyclonal Antibody (PACO01818) is a valuable tool for researchers studying the RASSF8 protein, a member of the RASSF family implicated in cell cycle regulation and tumor suppression. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RASSF8 protein, this antibody enables the detection and analysis of RASSF8 in various cell types, making it an ideal choice for studies in oncology and cell biology.RASSF8 is known to play a key role in cell division and growth regulation, making it a promising target for research into cancer and other diseases involving abnormal cell proliferation.
Understanding the functions and interactions of the RASSF8 protein is crucial for developing new therapeutic strategies for cancer treatment and potentially other related conditions. The RASSF8 Polyclonal Antibody offers reliable and accurate detection of RASSF8, facilitating further investigation into its functions and potential applications in biomedical research.
Antibody Name:
RASSF8 Antibody
Antibody SKU:
PACO01818
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Rat
Immunogen:
synthesized peptide derived from the Internal region of human RASSF8.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
