The RASSF6 Polyclonal Antibody (CAB5187) is a powerful tool for researchers studying the RASSF6 protein, a potential tumor suppressor involved in cell proliferation and apoptosis. This antibody, generated in rabbits, exhibits high specificity for human samples and has been rigorously tested for use in Western blot applications.RASSF6, a member of the Ras association domain family, is implicated in various cellular processes, including cell cycle regulation and DNA damage response. Dysregulation of RASSF6 expression has been linked to tumorigenesis and cancer progression, making it a promising target for cancer research and drug development.
By targeting the RASSF6 protein, researchers can gain valuable insights into its molecular functions and signaling pathways, paving the way for advancements in cancer therapy and personalized medicine. The RASSF6 Polyclonal Antibody is a valuable asset for studies investigating the role of RASSF6 in cancer biology and exploring its potential as a therapeutic target.
Product Name:
RASSF6 Rabbit Polyclonal Antibody
SKU:
CAB5187
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human RASSF6 (NP_001257320.1).
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms.
Purification Method:
Affinity purification
Gene ID:
166824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RASSF6 antibody (CAB5187) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
