The RASSF5 Polyclonal Antibody (CAB7389) is a powerful tool for researchers studying the RAS association domain family member 5 (RASSF5) protein. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RASSF5 protein, this antibody allows for the detection and analysis of RASSF5 in various cell types, making it ideal for investigations in cancer biology and cell signaling pathways.RASSF5, also known as Ras association domain-containing protein 5, is involved in regulating cell proliferation, apoptosis, and cell cycle progression. Dysregulation of RASSF5 has been implicated in various cancers and other diseases, making it a promising target for therapeutic interventions.
Understanding the function and expression levels of RASSF5 is crucial for unraveling its role in tumorigenesis and identifying potential treatment strategies.Overall, the RASSF5 Polyclonal Antibody (CAB7389) offers researchers a reliable tool for investigating the functions and interactions of RASSF5 in various biological processes. Its specificity and sensitivity make it a valuable asset for studies aiming to elucidate the molecular mechanisms underlying disease pathology and therapeutic development.
Product Name:
RASSF5 Rabbit Polyclonal Antibody
SKU:
CAB7389
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human RASSF5 (NP_872606.1).
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
83593
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RASSF5 antibody (CAB7389) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
