The RASSF5 Polyclonal Antibody (CAB12602) is a valuable tool for researchers studying the RASSF5 protein, a member of the Ras association domain family known for its tumor suppressor activity. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the RASSF5 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cancer biology and tumor suppression mechanisms.RASSF5, also called Ras association domain family member 5, plays a crucial role in regulating cell growth, apoptosis, and tumor development.
Its tumor suppressor function and involvement in signaling pathways make it a promising target for cancer research and drug development. Understanding the molecular mechanisms of RASSF5 can provide insights into tumorigenesis, metastasis, and potential therapeutic interventions for various cancers.Overall, the RASSF5 Polyclonal Antibody is a valuable tool for researchers seeking to explore the role of RASSF5 in cancer biology and uncover novel therapeutic strategies for cancer treatment. Its high specificity and sensitivity make it an essential component in studies aiming to unravel the complex functions of RASSF5 in cellular processes and oncogenic pathways.
Product Name:
RASSF5 Rabbit Polyclonal Antibody
SKU:
CAB12602
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human RASSF5 (NP_872606.1).
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
83593
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RASSF5 antibody (CAB12602) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
