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RASSF1A Monoclonal Antibody [P3F3AT] (CPAB0547)

SKU:
CPAB0547
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
P3F3AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

RASSF1A Monoclonal Antibody [P3F3AT] (CPAB0547)

The RASSF1A Polyclonal Antibody (CPAB0547) is a vital tool for researchers studying the RASSF1A protein, a tumor suppressor gene associated with various cancers and epigenetic alterations. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications.RASSF1A is known to be involved in cell cycle regulation, apoptosis, and DNA repair processes, making it a key player in tumor suppression mechanisms.

By targeting the RASSF1A protein, researchers can gain valuable insights into the molecular pathways underlying cancer development and progression.This antibody is suitable for use in immunology and cancer research studies, allowing for the detection and analysis of RASSF1A expression in a variety of cell types. Understanding the role of RASSF1A in tumorigenesis and potential therapeutic interventions is essential for developing targeted treatments for cancer patients.

Product Name:RASSF1A Antibody
Product Sku:CPAB0547
Size:5μg
Host Species:Mouse
Immunogen:Anti-human RASSF1A mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human RASSF1A amino acids 1-34 purified from Ecoli.
Clone:P3F3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:RASSF1A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:RASSF1A is a protein similar to the RAS effector proteins. Loss or altered expression of the RASSF1A gene has been linked to the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of the RASSF1A gene. The inactivation of the RASSF1A gene was found to be interconnected with the hypermethylation of its CpG-island promoter region. The RASSF1A protein was found to interact with DNA repair protein XPA. RASSF1A was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.
Synonyms:Ras association domain-containing protein 1, 123F2, RDA32, NORE2A, RASSF1A, REH3P21, RASSF1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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