The RASIP1 Polyclonal Antibody (CAB18466) is a valuable tool for researchers studying RASIP1, a protein involved in cell signaling and regulation of cellular processes. This antibody is produced in rabbits and has high reactivity with human samples, making it suitable for use in Western blot applications. By binding specifically to the RASIP1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and signal transduction pathways.
RASIP1, also known as Ras interacting protein 1, plays a crucial role in mediating intracellular signaling cascades and controlling cellular functions such as cell growth and migration. Dysregulation of RASIP1 has been linked to various diseases, including cancer and cardiovascular disorders, making it a promising target for therapeutic interventions. By studying the role of RASIP1 in these contexts, researchers can gain valuable insights into disease mechanisms and potentially identify new treatment strategies.
Product Name:
RASIP1 Rabbit Polyclonal Antibody
SKU:
CAB18466
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 635-785 of human RASIP1 (Q5U651).
cell-cell junction, Golgi stack, perinuclear region of cytoplasm
Calculated MW:
103kDa
Observed MW:
103kDa
Enables GTPase binding activity and protein homodimerization activity. Involved in several processes, including negative regulation of Rho protein signal transduction; negative regulation of Rho-dependent protein serine/threonine kinase activity; and positive regulation of integrin activation. Located in cell-cell junction. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
54922
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RASIP1 Rabbit pAb (CAB18466) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
