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RASGRP3 Rabbit Polyclonal Antibody (CAB7791)

SKU:
CAB7791
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 11 Anti-RASGRP3 Antibody CAB7791
  • Cell Biology Antibodies 11 Anti-RASGRP3 Antibody CAB7791
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RASGRP3 Rabbit Polyclonal Antibody
SKU:CAB7791
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 540-689 of human RASGRP3 (NP_056191.1).
Sequence:VLAC RRFA RAPS LSSG HGSL PGSP SLPP AQDE VFEF PGVT AGHR DLDS RAIT LVTG SSRK ISVR LQRA TTSQ ATQT EPVW SEAG WGDS GSHT FPKM KSKF HDKA AKDK GFAK WENE KPRV HAGV DVVD RGTE FELD QDEG EETR QDGE DG
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:GRP3; RASGRP3
Positive Sample:BT-474,A-549,Mouse heart,Mouse lung,Mouse thymus
Conjugate:Unconjugated
Cellular Localization:perinuclear region of cytoplasm, plasma membrane
Calculated MW:78kDa
Observed MW:78kDa

The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.

Purification Method:Affinity purification
Gene ID:25780
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using RASGRP3 antibody (CAB7791) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

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