The RasGRP3 Polyclonal Antibody (CAB7791) is a valuable tool for researchers studying RasGRP3, a crucial player in the Ras signaling pathway that regulates cell growth and proliferation. This antibody, produced in rabbits, specifically targets the RasGRP3 protein and has been validated for use in Western blot applications on human samples.RasGRP3 is involved in numerous cellular processes, including cell differentiation, survival, and migration, making it a key target for investigation in cancer research. By targeting RasGRP3, researchers can gain insights into the role of this protein in cancer development and progression, potentially leading to the identification of new therapeutic targets.
With its high reactivity and specificity for RasGRP3, this polyclonal antibody is an essential tool for researchers looking to unravel the intricate mechanisms of the Ras signaling pathway and its implications in diseases such as cancer. Unlocking the mysteries of RasGRP3 could pave the way for novel treatment strategies and advancements in personalized medicine.
Product Name:
RASGRP3 Rabbit Polyclonal Antibody
SKU:
CAB7791
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 540-689 of human RASGRP3 (NP_056191.1).
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.
Purification Method:
Affinity purification
Gene ID:
25780
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RASGRP3 antibody (CAB7791) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
