RASGRP2 Rabbit Polyclonal Antibody (CAB15381)
- SKU:
- CAB15381
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RASGRP2 Rabbit Polyclonal Antibody |
SKU: | CAB15381 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RASGRP2 (NP_722541.1). |
Sequence: | MAGT LDLD KGCT VEEL LRGC IEAF DDSG KVRD PQLV RMFL MMHP WYIP SSQL AAKL LHIY QQSR KDNS NSLQ VKTC HLVR YWIS AFPA EFDL NPEL AEQI KELK ALLD QEGN RRHS SLID IDSV PTYK WKRQ VTQR NPVG QKKR KMSL LFDH LEPM ELAE HLTY LEYR SFCK ILFQ DYHS FVTH GCTV DNPV LERF ISLF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | CDC25L; CALDAG-GEFI; RASGRP2 |
Positive Sample: | 293T,LO2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Peripheral membrane protein, cytosol, ruffle membrane, synapse, synaptosome. |
Calculated MW: | 69kDa |
Observed MW: | 69kDa |
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10235 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |