The RasGRP2 Polyclonal Antibody (CAB15381) is a versatile tool for researchers studying RasGRP2, a critical signaling protein involved in cell growth, differentiation, and proliferation. This antibody, produced in rabbits, shows high specificity and reactivity with human and other samples, making it an excellent choice for Western blot experiments.RasGRP2 is a key player in cellular signaling pathways, particularly in the regulation of immune responses and cell development. Its dysregulation has been linked to various diseases, including cancer and autoimmune disorders.
The RasGRP2 Polyclonal Antibody binds specifically to the RasGRP2 protein, allowing for precise detection and analysis in a variety of cell types.By using the RasGRP2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of RasGRP2 in health and disease. This antibody is an essential tool for studies in immunology, cancer biology, and other fields where RasGRP2 is a focal point of investigation.
Product Name:
RASGRP2 Rabbit Polyclonal Antibody
SKU:
CAB15381
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RASGRP2 (NP_722541.1).
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10235
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RASGRP2 Rabbit pAb (CAB15381) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
