The RASGEF1A Polyclonal Antibody (PAC063859) is a powerful tool for researchers studying RASGEF1A, a protein involved in cellular signaling pathways and implicated in various biological processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting RASGEF1A in human samples, making it a reliable choice for Western blot applications.RASGEF1A, also known as RasGEF Domain Family Member 1A, plays a crucial role in regulating Ras signaling, which is essential for cell growth, differentiation, and survival. Dysregulation of Ras signaling pathways has been linked to cancer and other diseases, highlighting the importance of studying RASGEF1A in both normal physiological processes and pathologies.
By using the RASGEF1A Polyclonal Antibody, researchers can accurately detect and analyze RASGEF1A expression in a variety of cell types, paving the way for deeper insights into its function and potential therapeutic implications. This antibody is an invaluable resource for studies in cell biology, cancer research, and drug development related to Ras signaling pathways.
Antibody Name:
RASGEF1A Antibody (PACO63859)
Antibody SKU:
PACO63859
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Ras-GEF domain-containing family member 1A protein (1-207AA)
Immunofluorescence staining of U251 cells with PACO63859 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.
Synonyms:
Ras-GEF domain-containing family member 1A, RASGEF1A
UniProt Protein Function:
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.
