The Rab45 Monoclonal Antibody is a specialized research tool designed for scientists studying the Rab45 protein, a key regulator of intracellular membrane trafficking. This antibody, derived from a single clone of immune cells, is highly specific to Rab45 and is validated for use in a variety of applications, including immunofluorescence and immunoprecipitation.Rab45 is a member of the Ras-related small GTPase family and plays a crucial role in controlling the transport of proteins and lipids within cells.
Dysregulation of Rab45 has been linked to various diseases, including cancer and neurodegenerative disorders, making it an important target for research in cell biology and disease mechanisms.By using the Rab45 Monoclonal Antibody, researchers can accurately detect and study the expression and localization of Rab45 in different cell types and experimental conditions. This antibody is a valuable tool for exploring the functions of Rab45 and its potential implications in health and disease.
Product Name:
RAB45 Monoclonal Antibody
SKU:
CAB21163
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RAB45 (NP_689786.2).
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene.
Purification Method:
Affinity purification
Gene ID:
158158
Clone Number:
ARC3022
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RAB45 Rabbit mAb (CAB21163) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
