The Rasal2 Polyclonal Antibody (CAB15120) is specifically designed for research involving Rasal2, a protein involved in cellular signaling pathways and implicated in various biological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to Rasal2, this antibody enables the detection and analysis of the protein in a wide range of cell types, making it ideal for studies in cell signaling, cancer research, and other areas of biomedical research.Rasal2 is a guanosine triphosphatase-activating protein that plays a crucial role in regulating Ras signaling, which is involved in cell proliferation, differentiation, and survival.
Dysregulation of Ras signaling pathways is often associated with various diseases, including cancer. Therefore, the Rasal2 Polyclonal Antibody is a valuable tool for researchers looking to investigate the role of Rasal2 in disease development and progression, as well as its potential as a therapeutic target. Understanding the function of Rasal2 at the molecular level is essential for the development of targeted therapies and precision medicine approaches in the treatment of Ras-related disorders.
Product Name:
RASAL2 Rabbit Polyclonal Antibody
SKU:
CAB15120
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 750-1040 of human RASAL2 (NP_733793.2).
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Purification Method:
Affinity purification
Gene ID:
9462
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using RASAL2 Rabbit pAb (CAB15120) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
