The RARG Monoclonal Antibody is a powerful tool for research involving the RARG protein, a key regulator of gene expression involved in various biological processes. This monoclonal antibody, produced using hybridoma technology, offers high specificity and sensitivity for detecting RARG in a variety of samples.RARG, a nuclear receptor transcription factor, plays a crucial role in regulating cell differentiation, proliferation, and apoptosis. It is known to be involved in multiple signaling pathways and has been linked to the development of cancer, metabolic disorders, and developmental abnormalities. By targeting RARG with this monoclonal antibody, researchers can gain valuable insights into its function and potential as a therapeutic target.
This antibody has been validated for use in various applications, including immunohistochemistry, flow cytometry, and Western blotting, allowing for versatile and reliable detection of RARG in different experimental settings. Its high specificity and sensitivity make it an ideal choice for studies in molecular biology, cancer research, and drug discovery.Overall, the RARG Monoclonal Antibody offers a valuable tool for researchers looking to explore the role of RARG in health and disease, providing a deeper understanding of its functions and potential implications for therapeutic interventions.
Product Name:
RARG Monoclonal Antibody
SKU:
CAB23233
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RARG (NP_000957.1).
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5916
Clone Number:
ARC59266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RARG Rabbit mAb (CAB23233) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
