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[KD Validated] RARG Polyclonal Antibody (CAB21785)

SKU:
CAB21785
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KD Validated] RARG Polyclonal Antibody
SKU:CAB21785
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RARG (NP_000957.1).
Sequence:MATN KERL FAAG ALGP GSGY PGAG FPFA FPGA LRGS PPFE MLSP SFRG LGQP DLPK EMAS LSVE TQST SS
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:RARC; NR1B3; RARgamma; [KD Validated] RARG
Positive Sample:MCF7,SK-BR-3
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:50kDa
Observed MW:48kDa

This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:5916
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of SK-BR-3 cells, using RARG antibody (CAB21785) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

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