The KD-Validated RARG Polyclonal Antibody is a valuable tool for research involving the retinoic acid receptor gamma (RARG), a nuclear receptor protein known for its involvement in gene regulation and cellular differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications.RARG is a key player in various biological processes such as embryonic development, immune response, and cell growth. Its dysregulation has been linked to diseases like cancer, metabolic disorders, and neurodegenerative conditions.
By targeting RARG with this polyclonal antibody, researchers can investigate its expression levels and localization in different cell types, shedding light on its role in health and disease.With its reliability and versatility, the KD-Validated RARG Polyclonal Antibody is an essential tool for studies in molecular biology, pharmacology, and toxicology. By enabling precise detection and analysis of RARG protein, this antibody opens up new possibilities for understanding its function and potential therapeutic implications in various pathological conditions.
Product Name:
[KD Validated] RARG Polyclonal Antibody
SKU:
CAB21785
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RARG (NP_000957.1).
Sequence:
MATN KERL FAAG ALGP GSGY PGAG FPFA FPGA LRGS PPFE MLSP SFRG LGQP DLPK EMAS LSVE TQST SS
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
RARC; NR1B3; RARgamma; [KD Validated] RARG
Positive Sample:
MCF7,SK-BR-3
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
50kDa
Observed MW:
48kDa
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5916
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of SK-BR-3 cells, using RARG antibody (CAB21785) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
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