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RARα Rabbit Polyclonal Antibody (CAB0370)

SKU:
CAB0370
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-RARA Antibody CAB0370
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-RARA Antibody CAB0370
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-RARA Antibody CAB0370
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-RARA Antibody CAB0370
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RARα Rabbit Polyclonal Antibody
SKU:CAB0370
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-457 of human RARα (NP_001019980.1).
Sequence:MYES VEVG GPTP NPFL VVDF YNQN RACL LPEK GLPA PGPY STPL RTPL WNGS NHSI ETQS SSSE EIVP SPPS PPPL PRIY KPCF VCQD KSSG YHYG VSAC EGCK GFFR RSIQ KNMV YTCH RDKN CIIN KVTR NRCQ YCRL QKCF EVGM SKES VRND RNKK KKEV PKPE CSES YTLT PEVG ELIE KVRK AHQE TFPA LCQL GKYT TNNS SEQR VSLD IDLW DKFS ELST KCII KTVE FAKQ LPGF TTLT IADQ ITLL KAAC LDIL ILRI CTRY TPEQ DTMT FSDG LTLN RTQM HNAG FGPL TDLV FAFA NQLL PLEM DDAE TGLL SAIC LICG DRQD LEQP DRVD MLQE PLLE ALKV YVRK RRPS RPHM FPKM LMKI TDLR SISA KGAE RVIT LKME IPGS MPPL IQEM LENS EGLD TLSG QPGG GGRD GGGL APPP GSCS PSLS PSSN RSSP ATHS P
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:RAR; NR1B1; RARalpha; RARα
Positive Sample:MCF7,K-562,Raji,THP-1,SH-SY5Y,Mouse testis,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:51kDa
Observed MW:60kDa

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

Purification Method:Affinity purification
Gene ID:5914
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RARα Rabbit pAb (CAB0370) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

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