The Raptor Polyclonal Antibody (CAB21756) is specifically designed for research involving Raptor, a key protein involved in the regulation of cell growth and metabolism. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By binding to the Raptor protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.Raptor, also known as regulatory-associated protein of mTOR, is a critical component of the mTOR signaling pathway, which plays a central role in controlling cell growth, proliferation, and survival.
Dysregulation of this pathway is associated with various diseases, including cancer, diabetes, and neurodegenerative disorders. By studying the function of Raptor, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the Raptor Polyclonal Antibody (CAB21756) offers researchers a reliable tool for investigating the role of Raptor in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset in advancing our understanding of mTOR signaling and its implications for human health.
Product Name:
Raptor Polyclonal Antibody
SKU:
CAB21756
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 888-1013 of human Raptor (NP_065812.1).
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57521
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Raptor Rabbit pAb (CAB21756) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer:3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
