The RapGEF4 Polyclonal Antibody (CAB4484) is a valuable tool for researchers studying RapGEF4, a protein involved in intracellular signaling pathways regulating cell growth and differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting RapGEF4 in human samples, making it ideal for Western blot applications.RapGEF4 is known for its role in mediating cellular responses to extracellular signals, particularly in processes such as cell migration and adhesion. Its dysregulation has been implicated in various diseases, including cancer and neurological disorders, highlighting the importance of studying this protein.
The RapGEF4 Polyclonal Antibody enables researchers to investigate the expression levels and localization of RapGEF4 in different cell types, providing valuable insights into its function and potential therapeutic relevance.In summary, the RapGEF4 Polyclonal Antibody (CAB4484) is a reliable tool for researchers interested in unraveling the complex roles of RapGEF4 in cellular signaling pathways and its implications in disease pathogenesis. Its high specificity and sensitivity make it a valuable asset for studies in cell biology, cancer research, and drug development.
Product Name:
RAPGEF4 Rabbit Polyclonal Antibody
SKU:
CAB4484
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human RAPGEF4 (NP_001093867.1).
Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane and regulation of postsynapse organization. Predicted to act upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway; regulation of exocytosis; and secretion by cell. Predicted to be located in plasma membrane. Predicted to be active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density. Implicated in autistic disorder.
Purification Method:
Affinity purification
Gene ID:
11069
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAPGEF4 antibody (CAB4484) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
