The Rapgef3 Polyclonal Antibody (CAB2199) is a valuable tool for researchers studying Rapgef3, a key signaling molecule involved in various cellular processes, including cell growth and proliferation. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications.Rapgef3, also known as Rap guanine nucleotide exchange factor 3, plays a crucial role in the regulation of signaling pathways that control cell behavior and function. By targeting Rapgef3 with this antibody, researchers can accurately detect and analyze the protein in different cell types, allowing for in-depth studies in cell biology and cancer research.
The significance of Rapgef3 in cellular signaling makes it a promising target for investigating various diseases, including cancer and neurological disorders. Understanding the function and regulation of Rapgef3 can provide valuable insights for the development of targeted therapies that modulate its activity in disease settings. By utilizing the Rapgef3 Polyclonal Antibody (CAB2199), researchers can further explore the role of Rapgef3 in health and disease, paving the way for new discoveries and treatment strategies.
Product Name:
Epac1/RAPGEF3 Rabbit Polyclonal Antibody
SKU:
CAB2199
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Epac1/Epac1/RAPGEF3 (NP_001092002.1).
Enables guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Involved in several processes, including positive regulation of protein modification process; regulation of actin cytoskeleton organization; and regulation of syncytium formation by plasma membrane fusion. Located in filopodium; lamellipodium; and microvillus. Colocalizes with cortical actin cytoskeleton and plasma membrane. Biomarker of congestive heart failure.
Purification Method:
Affinity purification
Gene ID:
10411
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Epac1/RAPGEF3 Rabbit pAb (CAB2199) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
