RAPGEF1 Rabbit Polyclonal Antibody (CAB16050)
- SKU:
- CAB16050
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | RAPGEF1 Rabbit Polyclonal Antibody |
SKU: | CAB16050 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 844-1095 of human RAPGEF1 (NP_941372.1). |
Sequence: | ARGV AARP GTLH DFHS HEIA EQLT LLDA ELFY KIEI PEVL LWAK EQNE EKSP NLTQ FTEH FNNM SYWV RSII MLQE KAQD RERL LLKF IKIM KHLR KLNN FNSY LAIL SALD SAPI RRLE WQKQ TSEG LAEY CTLI DSSS SFRA YRAA LSEV EPPC IPYL GLIL QDLT FVHL GNPD YIDG KVNF SKRW QQFN ILDS MRCF QQAH YDMR RNDD IINF FNDF SDHL AEEA LWEL SLKI KPRN ITRR KTDR EEKT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | C3G; GRF2; RAPGEF1 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Early endosome |
Calculated MW: | 121kDa |
Observed MW: | 120kDa |
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 2889 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |