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RAP1GDS1 Antibody (PACO11718)

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SKU:
PACO11718
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€669

Description

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RAP1GDS1 Antibody (PACO11718)

The RAP1GDS1 Monoclonal Antibody (PAC011718) is a valuable tool for researchers studying RAP1GDS1, a protein involved in cell signaling and regulation of various cellular processes. This antibody, produced in mice, is highly specific to human samples and is suitable for use in techniques such as Western blot and immunohistochemistry.RAP1GDS1, also known as RAP1 GDP/GTP exchange factor 1, plays a crucial role in mediating the function of the RAP1 protein, which is involved in cell adhesion, migration, and proliferation. By targeting RAP1GDS1, researchers can explore its role in signaling pathways related to cell growth, differentiation, and apoptosis.

This antibody enables precise detection and analysis of RAP1GDS1 in different cell types, providing valuable insights into its function and potential implications in various diseases such as cancer, cardiovascular disorders, and neurological conditions. By understanding the mechanisms involving RAP1GDS1, researchers can potentially identify novel therapeutic targets for intervention in these diseases.

Antibody Name:RAP1GDS1 Antibody (PACO11718)
Antibody SKU:PACO11718
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human RAP1GDS1
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:RAP1, GTP-GDP dissociation stimulator 1;RAP1GDS1;GDS1;MGC118859;MGC118861;SmgGDS ;
UniProt Protein Function:RAP1GDS1: Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GEFs, misc.; GEFs

Chromosomal Location of Human Ortholog: 4q23-q25

Cellular Component: cytosol; endoplasmic reticulum; mitochondrion

Molecular Function:protein binding

Biological Process: elevation of mitochondrial calcium ion concentration; positive regulation of GTPase activity; reduction of endoplasmic reticulum calcium ion concentration; small GTPase mediated signal transduction

NCBI Summary:The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010]
UniProt Code:P52306
NCBI GenInfo Identifier:212276504
NCBI Gene ID:5910
NCBI Accession:P52306.3
UniProt Secondary Accession:P52306,Q499L7, Q4KMV2, Q4QQI8, Q9BUW9, Q9BUX6, Q9NYM2 Q9NZA8, E9PH06, G5E9P9,
UniProt Related Accession:P52306
Molecular Weight:56,536 Da
NCBI Full Name:Rap1 GTPase-GDP dissociation stimulator 1
NCBI Synonym Full Names:Rap1 GTPase-GDP dissociation stimulator 1
NCBI Official Symbol:RAP1GDS1  
NCBI Official Synonym Symbols:GDS1; SmgGDS  
NCBI Protein Information:rap1 GTPase-GDP dissociation stimulator 1
UniProt Protein Name:Rap1 GTPase-GDP dissociation stimulator 1
UniProt Synonym Protein Names:Exchange factor smgGDS; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein
Protein Family:Rap1 GTPase-GDP dissociation stimulator
UniProt Gene Name:RAP1GDS1  
UniProt Entry Name:GDS1_HUMAN

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