The RAP1B Polyclonal Antibody (CAB12925) is a valuable tool for researchers studying the RAP1B protein, which plays a key role in regulating cell adhesion, cell polarity, and cell migration. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.RAP1B is a member of the RAS family of small GTPases and is involved in various cellular processes, including integrin activation, cell adhesion, and cell migration.
Dysregulation of RAP1B activity has been associated with cancer progression and metastasis, making it an important target for cancer research.By using the RAP1B Polyclonal Antibody, researchers can detect and analyze the expression of RAP1B in different cell types, providing valuable insights into its function in normal and disease states. This antibody is a valuable tool for studies in cell biology, cancer research, and drug development aimed at targeting RAP1B signaling pathways.
Product Name:
Rap1B Rabbit Polyclonal Antibody
SKU:
CAB12925
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human Rap1B (NP_056461.1).
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.
Purification Method:
Affinity purification
Gene ID:
5908
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Rap1B Rabbit pAb (CAB12925) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
