Rap1A Rabbit Polyclonal Antibody (CAB0975)
- SKU:
- CAB0975
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | Rap1A Rabbit Polyclonal Antibody |
SKU: | CAB0975 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 39-138 of human Rap1A (NP_002875.1). |
Sequence: | SYRK QVEV DCQQ CMLE ILDT AGTE QFTA MRDL YMKN GQGF ALVY SITA QSTF NDLQ DLRE QILR VKDT EDVP MILV GNKC DLED ERVV GKEQ GQNL ARQW |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21; 1A |
Positive Sample: | 293T,U-87MG,HL-60 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Early endosome, Lipid-anchor, perinuclear region. |
Calculated MW: | 21kDa |
Observed MW: | 21kDa |
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5906 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |