The RANGAP1 Polyclonal Antibody (CAB5381) is an essential tool for researchers studying the RANGAP1 protein, which plays a critical role in the regulation of nuclear transport and cell division. This antibody is raised in rabbits and has been shown to be highly reactive with human samples, making it a reliable choice for experiments involving RANGAP1.Validated for use in Western blot applications, the RANGAP1 Polyclonal Antibody binds specifically to the RANGAP1 protein, allowing for accurate detection and analysis in a variety of cell types. This makes it ideal for studies in cell biology and cancer research, where understanding the function of RANGAP1 is key to uncovering its role in disease progression.
RANGAP1 is known for its involvement in the control of the mitotic spindle during cell division, making it a crucial player in maintaining genomic stability. Dysregulation of RANGAP1 expression has been linked to various human diseases, including cancer and neurodegenerative disorders. By utilizing the RANGAP1 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
RanGAP1 Rabbit Polyclonal Antibody
SKU:
CAB5381
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 398-587 of human RanGAP1 (NP_002874.1).
This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5905
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RanGAP1 antibody (CAB5381) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
